Cannabidiol, or CBD, is typically extremely safe. That being said, many prescription and over the counter drugs can potentially interact with CBD. This can cause levels of medications to become too high or too low, both of which can lead to risks. If you are taking any medications at all, you should always consult with your physician before adding CBD products to your regimen.
The below list was compiled from Medscape. Medscape is a resource that physicians use to look up drugs, check interactions, side effects, dosage, etc. This list is for your information/education only and is not intended in any way to be medical advice. Always consult your physician if taking ANY medications. This list may not encompass every drug that can have an interaction with CBD.
Meds known to potentially interact with CBD:
abiraterone
abiraterone can increase the level or effect of cannabidiol by affecting hepatic enzyme CYP2C19 metabolism. Consult your physician before adding CBD products.
ambrisentan
cannabidiol will increase the level or effect of ambrisentan by affecting hepatic enzyme CYP2C19 metabolism.
amiodarone
amiodarone will increase the level or effect of cannabidiol by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
cannabidiol will increase the level or effect of amiodarone by affecting hepatic enzyme CYP2C19 metabolism.
cannabidiol will increase the level or effect of amiodarone by decreasing metabolism.
amobarbital
amobarbital will decrease the level or effect of cannabidiol by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
apalutamide
cannabidiol will increase the level or effect of apalutamide by decreasing metabolism. Modify Therapy/Monitor Closely. Cannabidiol may potentially inhibit CYP2C8 activity. Consider reducing the dose when concomitantly using CYP2C8 substrates.
aprepitant
aprepitant will increase the level or effect of cannabidiol by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
armodafinil
armodafinil will increase the level or effect of cannabidiol by affecting hepatic enzyme CYP2C19 metabolism.
atazanavir
atazanavir will increase the level or effect of cannabidiol by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
bicalutamide
bicalutamide will increase the level or effect of cannabidiol by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
bortezomib
bortezomib will increase the level or effect of cannabidiol by affecting hepatic enzyme CYP2C19 metabolism.
cannabidiol will increase the level or effect of bortezomib by affecting hepatic enzyme CYP2C19 metabolism.
bosentan
cannabidiol will increase the level or effect of bosentan by decreasing metabolism.
bupropion
cannabidiol, bupropion. affecting hepatic enzyme CYP2B6 metabolism.
butabarbital
butabarbital will decrease the level or effect of cannabidiol by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
butalbital
butalbital will decrease the level or effect of cannabidiol by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
carbamazepine
carbamazepine will decrease the level or effect of cannabidiol by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
carisoprodol
cannabidiol will increase the level or effect of carisoprodol by affecting hepatic enzyme CYP2C19 metabolism.
carvedilol
cannabidiol will increase the level or effect of carvedilol by decreasing metabolism.
celecoxib
cannabidiol will increase the level or effect of celecoxib by decreasing metabolism.
ceritinib
ceritinib will increase the level or effect of cannabidiol by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
chloramphenicol
chloramphenicol will increase the level or effect of cannabidiol by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
chloramphenicol will increase the level or effect of cannabidiol by affecting hepatic enzyme CYP2C19 metabolism.
chlorpropamide
cannabidiol will increase the level or effect of chlorpropamide by decreasing metabolism.
citalopram
cannabidiol will increase the level or effect of citalopram by affecting hepatic enzyme CYP2C19 metabolism.
clarithromycin
clarithromycin will increase the level or effect of cannabidiol by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
clobazam
cannabidiol will increase the level or effect of clobazam by affecting hepatic enzyme CYP2C19 metabolism.
clomipramine
cannabidiol will increase the level or effect of clomipramine by affecting hepatic enzyme CYP2C19 metabolism.
clotrimazole
clotrimazole will increase the level or effect of cannabidiol by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
clozapine
clozapine will increase the level or effect of cannabidiol by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
cobicistat
cobicistat will increase the level or effect of cannabidiol by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
conivaptan
conivaptan will increase the level or effect of cannabidiol by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
conjugated estrogens
cannabidiol, conjugated estrogens. affecting hepatic enzyme CYP1A2 metabolism.
conjugated estrogens, vaginal
cannabidiol, conjugated estrogens, vaginal. affecting hepatic enzyme CYP1A2 metabolism.
crizotinib
crizotinib will increase the level or effect of cannabidiol by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
cyclobenzaprine
cannabidiol, cyclobenzaprine. affecting hepatic enzyme CYP1A2 metabolism.
cyclophosphamide
cannabidiol, cyclophosphamide. affecting hepatic enzyme CYP2B6 metabolism.
cyclosporine
cyclosporine will increase the level or effect of cannabidiol by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
dabrafenib
dabrafenib will decrease the level or effect of cannabidiol by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
cannabidiol will increase the level or effect of dabrafenib by decreasing metabolism.
dacarbazine
cannabidiol, dacarbazine. affecting hepatic enzyme CYP1A2 metabolism.
dapsone
cannabidiol will increase the level or effect of dapsone by decreasing metabolism.
darunavir
darunavir will increase the level or effect of cannabidiol by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
dasabuvir
cannabidiol will increase the level or effect of dasabuvir by decreasing metabolism.
delavirdine
delavirdine will increase the level or effect of cannabidiol by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
delavirdine will increase the level or effect of cannabidiol by affecting hepatic enzyme CYP2C19 metabolism.
desipramine
desipramine will increase the level or effect of cannabidiol by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
dexlansoprazole
dexlansoprazole will increase the level or effect of cannabidiol by affecting hepatic enzyme CYP2C9/10 metabolism.
cannabidiol will increase the level or effect of dexlansoprazole by affecting hepatic enzyme CYP2C19 metabolism.
diazepam
cannabidiol will increase the level or effect of diazepam by affecting hepatic enzyme CYP2C19 metabolism.
diclofenac
cannabidiol will increase the level or effect of diclofenac by decreasing metabolism.
diltiazem
diltiazem will increase the level or effect of cannabidiol by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
doxepin cream
cannabidiol, doxepin cream. affecting hepatic enzyme CYP1A2 metabolism.
doxycycline
doxycycline will increase the level or effect of cannabidiol by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
dronabinol
cannabidiol will increase the level or effect of dronabinol by decreasing metabolism.
dronedarone
dronedarone will increase the level or effect of cannabidiol by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
duloxetine
cannabidiol, duloxetine. affecting hepatic enzyme CYP1A2 metabolism.
efavirenz
efavirenz will increase the level or effect of cannabidiol by affecting hepatic enzyme CYP2C19 metabolism.
efavirenz will decrease the level or effect of cannabidiol by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
cannabidiol, efavirenz. affecting hepatic enzyme CYP2B6 metabolism.
enzalutamide
enzalutamide will decrease the level or effect of cannabidiol by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
enzalutamide will decrease the level or effect of cannabidiol by affecting hepatic enzyme CYP2C19 metabolism.
cannabidiol will increase the level or effect of enzalutamide by decreasing metabolism. Cannabidiol may potentially inhibit CYP2C8 activity.
erythromycin base
erythromycin base will increase the level or effect of cannabidiol by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
erythromycin ethylsuccinate
erythromycin ethylsuccinate will increase the level or effect of cannabidiol by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
erythromycin lactobionate
erythromycin lactobionate will increase the level or effect of cannabidiol by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
erythromycin stearate
erythromycin stearate will increase the level or effect of cannabidiol by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
escitalopram
cannabidiol will increase the level or effect of escitalopram by affecting hepatic enzyme CYP2C19 metabolism.
esketamine intranasal
esketamine intranasal, cannabidiol. Either increases toxicity of the other by sedation.
eslicarbazepine acetate
eslicarbazepine acetate will increase the level or effect of cannabidiol by affecting hepatic enzyme CYP2C19 metabolism.
esomeprazole
esomeprazole will increase the level or effect of cannabidiol by affecting hepatic enzyme CYP2C19 metabolism.
cannabidiol will increase the level or effect of esomeprazole by affecting hepatic enzyme CYP2C19 metabolism.
estradiol
cannabidiol, estradiol. affecting hepatic enzyme CYP1A2 metabolism.
estrogens conjugated synthetic
cannabidiol, estrogens conjugated synthetic. affecting hepatic enzyme CYP1A2 metabolism.
etravirine
etravirine will increase the level or effect of cannabidiol by affecting hepatic enzyme CYP2C19 metabolism.
etravirine will decrease the level or effect of cannabidiol by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
cannabidiol will increase the level or effect of etravirine by affecting hepatic enzyme CYP2C19 metabolism.
cannabidiol will increase the level or effect of etravirine by decreasing metabolism.
fenofibrate
cannabidiol will increase the level or effect of fenofibrate. Cannabidiol may potentially inhibit UGT1A9 activity.
flibanserin
cannabidiol will increase the level or effect of flibanserin by affecting hepatic enzyme CYP2C19 metabolism.
fluconazole
fluconazole will increase the level or effect of cannabidiol by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
fluconazole will increase the level or effect of cannabidiol by affecting hepatic enzyme CYP2C19 metabolism.
fluoxetine
fluoxetine will increase the level or effect of cannabidiol by affecting hepatic enzyme CYP2C19 metabolism.
cannabidiol will increase the level or effect of fluoxetine by decreasing metabolism.
flutamide
cannabidiol, flutamide. affecting hepatic enzyme CYP1A2 metabolism.
fluvastatin
cannabidiol will increase the level or effect of fluvastatin by decreasing metabolism.
fluvoxamine
fluvoxamine will increase the level or effect of cannabidiol by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
fluvoxamine will increase the level or effect of cannabidiol by affecting hepatic enzyme CYP2C19 metabolism.
cannabidiol, fluvoxamine. affecting hepatic enzyme CYP1A2 metabolism.
fosamprenavir
fosamprenavir will increase the level or effect of cannabidiol by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
fosphenytoin
fosphenytoin will decrease the level or effect of cannabidiol by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
cannabidiol will increase the level or effect of fosphenytoin by affecting hepatic enzyme CYP2C19 metabolism.
cannabidiol will increase the level or effect of fosphenytoin by decreasing metabolism.
fostamatinib
fostamatinib will increase the level or effect of cannabidiol by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
gemfibrozil
gemfibrozil will increase the level or effect of cannabidiol by affecting hepatic enzyme CYP2C19 metabolism.
cannabidiol will increase the level or effect of gemfibrozil. Cannabidiol may potentially inhibit UGT2B7 activity.
glimepiride
cannabidiol will increase the level or effect of glimepiride by decreasing metabolism.
glipizide
cannabidiol will increase the level or effect of glipizide by decreasing metabolism.
glyburide
cannabidiol will increase the level or effect of glyburide by decreasing metabolism.
grapefruit
grapefruit will increase the level or effect of cannabidiol by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
haloperidol
haloperidol will increase the level or effect of cannabidiol by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
idelalisib
idelalisib will increase the level or effect of cannabidiol by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
ifosfamide
cannabidiol will increase the level or effect of ifosfamide by affecting hepatic enzyme CYP2C19 metabolism.
iloperidone
iloperidone will increase the level or effect of cannabidiol by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
imatinib
imatinib will increase the level or effect of cannabidiol by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
cannabidiol will increase the level or effect of imatinib by decreasing metabolism.
imipramine
cannabidiol will increase the level or effect of imipramine by affecting hepatic enzyme CYP2C19 metabolism.
indinavir
indinavir will increase the level or effect of cannabidiol by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
irinotecan
cannabidiol, irinotecan. affecting hepatic enzyme CYP2B6 metabolism.
isoniazid
isoniazid will increase the level or effect of cannabidiol by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
isoniazid will increase the level or effect of cannabidiol by affecting hepatic enzyme CYP2C19 metabolism.
isotretinoin
cannabidiol will increase the level or effect of isotretinoin by decreasing metabolism.
itraconazole
itraconazole will increase the level or effect of cannabidiol by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
ketamine
cannabidiol will increase the level or effect of ketamine by decreasing metabolism.
ketoconazole
ketoconazole will increase the level or effect of cannabidiol by affecting hepatic enzyme CYP2C19 metabolism.
lacosamide
cannabidiol will increase the level or effect of lacosamide by decreasing metabolism.
lamotrigine
cannabidiol will increase the level or effect of lamotrigine. Cannabidiol may potentially inhibit UGT2B7 activity.
lansoprazole
lansoprazole will increase the level or effect of cannabidiol by affecting hepatic enzyme CYP2C19 metabolism.
cannabidiol will increase the level or effect of lansoprazole by affecting hepatic enzyme CYP2C19 metabolism.
lapatinib
lapatinib will increase the level or effect of cannabidiol by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
lesinurad
cannabidiol will increase the level or effect of lesinurad by decreasing metabolism. Cannabidiol may potentially inhibit CYP2C9 activity.
letermovir
letermovir will increase the level or effect of cannabidiol by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
lidocaine
cannabidiol, lidocaine. affecting hepatic enzyme CYP1A2 metabolism.
lopinavir
lopinavir will increase the level or effect of cannabidiol by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
loratadine
loratadine will increase the level or effect of cannabidiol by affecting hepatic enzyme CYP2C19 metabolism.
lorazepam
cannabidiol will increase the level or effect of lorazepam by decreasing metabolism. Cannabidiol may potentially inhibit UGT2B7 activity.
losartan
cannabidiol will increase the level or effect of losartan by decreasing metabolism.
lumacaftor/ivacaftor
lumacaftor/ivacaftor will decrease the level or effect of cannabidiol by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
mephobarbital
cannabidiol will increase the level or effect of mephobarbital by affecting hepatic enzyme CYP2C19 metabolism.
mestranol
cannabidiol will decrease the level or effect of mestranol by decreasing metabolism.
metaxalone
cannabidiol, metaxalone affecting hepatic enzyme CYP1A2 metabolism.
methadone
cannabidiol will increase the level or effect of methadone by decreasing metabolism. Cannabidiol may potentially inhibit CYP2C8 activity.
methsuximide
cannabidiol will increase the level or effect of methsuximide by affecting hepatic enzyme CYP2C19 metabolism.
metronidazole
metronidazole will increase the level or effect of cannabidiol by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
mexiletine
cannabidiol, mexiletine. affecting hepatic enzyme CYP1A2 metabolism.
miconazole oral
miconazole oral will increase the level or effect of cannabidiol by affecting hepatic enzyme CYP2C19 metabolism.
cannabidiol will increase the level or effect of miconazole oral by decreasing metabolism.
mifepristone
mifepristone will increase the level or effect of cannabidiol by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
mirtazapine
cannabidiol, mirtazapine. affecting hepatic enzyme CYP1A2 metabolism.
mitotane
mitotane will decrease the level or effect of cannabidiol by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
modafinil
modafinil will increase the level or effect of cannabidiol by affecting hepatic enzyme CYP2C19 metabolism.
cannabidiol will increase the level or effect of modafinil by affecting hepatic enzyme CYP2C19 metabolism.
montelukast
cannabidiol will increase the level or effect of montelukast by decreasing metabolism. Cannabidiol may potentially inhibit CYP2C9 activity.
morphine
cannabidiol will increase the level or effect of morphine. Cannabidiol may potentially inhibit UGT2B7 activity.
nafcillin
nafcillin will decrease the level or effect of cannabidiol by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
nateglinide
cannabidiol will increase the level or effect of nateglinide by decreasing metabolism. Cannabidiol may potentially inhibit CYP2C9 activity.
nefazodone
nefazodone will increase the level or effect of cannabidiol by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
nelfinavir
nelfinavir will increase the level or effect of cannabidiol by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
cannabidiol will increase the level or effect of nelfinavir by affecting hepatic enzyme CYP2C19 metabolism.
netupitant/palonosetron
netupitant/palonosetron will increase the level or effect of cannabidiol by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
nevirapine
nevirapine will decrease the level or effect of cannabidiol by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
nicardipine
nicardipine will increase the level or effect of cannabidiol by affecting hepatic enzyme CYP2C19 metabolism.
olanzapine
cannabidiol, olanzapine. affecting hepatic enzyme CYP1A2 metabolism.
ombitasvir/paritaprevir/ritonavir
cannabidiol will increase the level or effect of ombitasvir/paritaprevir/ritonavir by decreasing metabolism. Cannabidiol may potentially inhibit CYP2C8 activity.
ombitasvir/paritaprevir/ritonavir & dasabuvir
cannabidiol will increase the level or effect of ombitasvir/paritaprevir/ritonavir & dasabuvir by decreasing metabolism.
omeprazole
omeprazole will increase the level or effect of cannabidiol by affecting hepatic enzyme CYP2C19 metabolism.
cannabidiol will increase the level or effect of omeprazole by affecting hepatic enzyme CYP2C19 metabolism.
osimertinib
osimertinib will increase the level or effect of cannabidiol by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
ospemifene
cannabidiol will increase the level or effect of ospemifene by affecting hepatic enzyme CYP2C19 metabolism.
cannabidiol will increase the level or effect of ospemifene by decreasing metabolism. Cannabidiol may potentially inhibit CYP2C9 activity.
oxcarbazepine
oxcarbazepine will decrease the level or effect of cannabidiol by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
paclitaxel
cannabidiol will increase the level or effect of paclitaxel by decreasing metabolism.
paclitaxel protein bound
cannabidiol will increase the level or effect of paclitaxel protein bound by decreasing metabolism. Cannabidiol may potentially inhibit CYP2C8 activity.
pantoprazole
pantoprazole will increase the level or effect of cannabidiol by affecting hepatic enzyme CYP2C19 metabolism.
cannabidiol will increase the level or effect of pantoprazole by affecting hepatic enzyme CYP2C19 metabolism.
pentamidine
cannabidiol will increase the level or effect of pentamidine by affecting hepatic enzyme CYP2C19 metabolism.
pentobarbital
pentobarbital will decrease the level or effect of cannabidiol by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
phenobarbital
phenobarbital will decrease the level or effect of cannabidiol by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
cannabidiol will increase the level or effect of phenobarbital by affecting hepatic enzyme CYP2C19 metabolism.
phenytoin
phenytoin will decrease the level or effect of cannabidiol by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
cannabidiol will increase the level or effect of phenytoin by affecting hepatic enzyme CYP2C19 metabolism.
cannabidiol will increase the level or effect of phenytoin by decreasing metabolism. Cannabidiol may potentially inhibit CYP2C9 activity.
pimozide
cannabidiol, pimozide. affecting hepatic enzyme CYP1A2 metabolism.
pioglitazone
cannabidiol will increase the level or effect of pioglitazone by decreasing metabolism. Cannabidiol may potentially inhibit CYP2C8 activity.
pirfenidone
cannabidiol, pirfenidone. affecting hepatic enzyme CYP1A2 metabolism.
pomalidomide
cannabidiol, pomalidomide. affecting hepatic enzyme CYP1A2 metabolism.
posaconazole
posaconazole will increase the level or effect of cannabidiol by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
progesterone intravaginal gel
cannabidiol will increase the level or effect of progesterone intravaginal gel by affecting hepatic enzyme CYP2C19 metabolism.
progesterone micronized
cannabidiol will increase the level or effect of progesterone micronized by affecting hepatic enzyme CYP2C19 metabolism.
propofol
propofol will increase the level or effect of cannabidiol by affecting hepatic enzyme CYP2C19 metabolism.
cannabidiol will increase the level or effect of propofol by decreasing metabolism. Cannabidiol may potentially inhibit CYP2C9 activity.
cannabidiol will increase the level or effect of propofol. Cannabidiol may potentially inhibit UGT1A9 activity.
propranolol
cannabidiol, propranolol. affecting hepatic enzyme CYP1A2 metabolism.
quinupristin/dalfopristin
quinupristin/dalfopristin will increase the level or effect of cannabidiol by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
rabeprazole
rabeprazole will increase the level or effect of cannabidiol by affecting hepatic enzyme CYP2C19 metabolism.
cannabidiol will increase the level or effect of rabeprazole by affecting hepatic enzyme CYP2C19 metabolism.
ramelteon
cannabidiol, ramelteon. affecting hepatic enzyme CYP1A2 metabolism.
rasagiline
cannabidiol, rasagiline. affecting hepatic enzyme CYP1A2 metabolism.
repaglinide
cannabidiol will increase the level or effect of repaglinide by decreasing metabolism. Cannabidiol may potentially inhibit CYP2C8 activity.
ribociclib
ribociclib will increase the level or effect of cannabidiol by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
rifampin
rifampin will decrease the level or effect of cannabidiol by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
cannabidiol, rifampin. affecting hepatic enzyme CYP2B6 metabolism.
rifapentine
rifapentine will decrease the level or effect of cannabidiol by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
riluzole
cannabidiol, riluzole. affecting hepatic enzyme CYP1A2 metabolism.
riociguat
cannabidiol will increase the level or effect of riociguat by decreasing metabolism.
ritonavir
ritonavir will increase the level or effect of cannabidiol by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
ropinirole
cannabidiol, ropinirole. affecting hepatic enzyme CYP1A2 metabolism.
ropivacaine
cannabidiol, ropivacaine. affecting hepatic enzyme CYP1A2 metabolism.
rosiglitazone
cannabidiol will increase the level or effect of rosiglitazone by decreasing metabolism. Cannabidiol may potentially inhibit CYP2C8 activity.
saquinavir
saquinavir will increase the level or effect of cannabidiol by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
schisandra
schisandra will increase the level or effect of cannabidiol by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
secobarbital
secobarbital will decrease the level or effect of cannabidiol by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
selegiline
cannabidiol, selegiline. affecting hepatic enzyme CYP2B6 metabolism.
selexipag
cannabidiol will increase the level or effect of selexipag by decreasing metabolism.
sertraline
sertraline will increase the level or effect of cannabidiol by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
cannabidiol will increase the level or effect of sertraline by affecting hepatic enzyme CYP2C19 metabolism.
St John's Wort
St John’s Wort will decrease the level or effect of cannabidiol by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
sulfadiazine
cannabidiol will increase the level or effect of sulfadiazine by decreasing metabolism. Cannabidiol may potentially inhibit CYP2C9 activity.
sulfisoxazole
cannabidiol will increase the level or effect of sulfisoxazole by decreasing metabolism. Cannabidiol may potentially inhibit CYP2C9 activity.
tacrine
cannabidiol, tacrine. affecting hepatic enzyme CYP1A2 metabolism.
tamoxifen
cannabidiol will increase the level or effect of tamoxifen by decreasing metabolism. Cannabidiol may potentially inhibit CYP2C9 activity.
tasimelteon
cannabidiol, tasimelteon. affecting hepatic enzyme CYP1A2 metabolism.
tetracycline
tetracycline will increase the level or effect of cannabidiol by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
theophylline
cannabidiol, theophylline. affecting hepatic enzyme CYP1A2 metabolism.
thiothixene
cannabidiol, thiothixene. affecting hepatic enzyme CYP1A2 metabolism.
ticlopidine
ticlopidine will increase the level or effect of cannabidiol by affecting hepatic enzyme CYP2C19 metabolism.
tipranavir
tipranavir will increase the level or effect of cannabidiol by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
tizanidine
cannabidiol, tizanidine. affecting hepatic enzyme CYP1A2 metabolism.
tofacitinib
cannabidiol will increase the level or effect of tofacitinib by affecting hepatic enzyme CYP2C19 metabolism.
tolbutamide
cannabidiol will increase the level or effect of tolbutamide by decreasing metabolism. Cannabidiol may potentially inhibit CYP2C9 activity.
torsemide
cannabidiol will increase the level or effect of torsemide by decreasing metabolism. Cannabidiol may potentially inhibit CYP2C9 activity.
tranylcypromine
tranylcypromine will increase the level or effect of cannabidiol by affecting hepatic enzyme CYP2C19 metabolism.
treprostinil
cannabidiol will increase the level or effect of treprostinil by decreasing metabolism. Cannabidiol may potentially inhibit CYP2C8 activity.
tretinoin
cannabidiol will increase the level or effect of tretinoin by decreasing metabolism. Cannabidiol may potentially inhibit CYP2C8 activity.
trifluoperazine
cannabidiol, trifluoperazine. affecting hepatic enzyme CYP1A2 metabolism.
trimethoprim
cannabidiol will increase the level or effect of trimethoprim by decreasing metabolism. Cannabidiol may potentially inhibit CYP2C9 activity.
trimipramine
cannabidiol will increase the level or effect of trimipramine by affecting hepatic enzyme CYP2C19 metabolism.
velpatasvir
cannabidiol, velpatasvir. affecting hepatic enzyme CYP2B6 metabolism.
cannabidiol will increase the level or effect of velpatasvir by decreasing metabolism. Cannabidiol may potentially inhibit CYP2C8 activity.
verapamil
verapamil will increase the level or effect of cannabidiol by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
voriconazole
voriconazole will increase the level or effect of cannabidiol by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
voriconazole will increase the level or effect of cannabidiol by affecting hepatic enzyme CYP2C19 metabolism.
cannabidiol will increase the level or effect of voriconazole by affecting hepatic enzyme CYP2C19 metabolism.
cannabidiol will increase the level or effect of voriconazole by decreasing metabolism. Cannabidiol may potentially inhibit CYP2C9 activity.
voxilaprevir
cannabidiol, voxilaprevir. affecting hepatic enzyme CYP1A2 metabolism.
cannabidiol will increase the level or effect of voxilaprevir by decreasing metabolism. Cannabidiol may potentially inhibit CYP2C8 activity.
warfarin
cannabidiol will increase the level or effect of warfarin by decreasing metabolism. Cannabidiol may potentially inhibit CYP2C9 activity.
zafirlukast
cannabidiol will increase the level or effect of zafirlukast by decreasing metabolism. Cannabidiol may potentially inhibit CYP2C9 activity.
